Andropause, the so-called male menopause is characterized by the retreat of the key male hormone testosterone. As a man ages, his testosterone levels may be down by 40% by his mid-forties. Lifestyle factors such as excessive stress, weight gain, and lack of exercise can accelerate the decline of testosterone. 

Testosterone is the hormone that is responsible for stamina, strength, drive, and virility in men.Restoring hormone balance involves identifying the hidden imbalances that contribute to symptoms of low T in men. 

High Estrogen- Weight gain, increased chest and belly fat, & excessive need to urinate (BPH).

High Cortisol- low energy, sugar carvings, poor exercise tolerance or recovery, chronic fatigue,& low immune reserves. 

Thyroid imbalance. This condition mimics symptoms of low T. 

High DHT results in excessive need to urinate (BPH).

Symptoms of low T includes:

  • Low sex drive
  • Sexual dysfunction- erectile dysfunction and infertility
  • Increased body fat
  • Decreased bone mass
  • Loss of muscle mass
  • Decreased strength, stamina, and energy
  • Depression, irritability
  • Lack of drive and motivation
  • Poor memory and mental focus

Treatment of low T may include nutritional, herbal supplements, diet and lifestyle modification, and bioidentical hormone therapy. Testosterone, DHEA, and  androstenedione are androgens which are a group of hormones that regulate the development and maintenance of male characteristics. They are synthesized from cholesterol and produced primarily in the testes and to a much lesser extent in the adrenal glands, fat and muscle cells. The presence of aromatase which is an enzyme responsible for the conversion of androgens to estrogen has been reported to be a cause of prepubertal gynecomastia (manboob), short stature, infertility in men, and erectile dysfunction. Aromatization, or conversion of testosterone to estrogen can also have the deleterious consequence of excess estrogen which can further metabolize to 16-alpha-hydroxyestrone that is linked to prostate cancer. 

Aromatase is located in cells in the adrenal glands, ovaries, testes, fat tissue and brain.Since abdominal fat tissue has more cells per mass unit, men who have truncal obesity tend to have higher rates of testosterone to estrogen conversion.  

While hormone supplementation may restore optimal hormone levels, there are many effective ways to decrease the activity of aromatase and exposures to estrogens. 

  • Limit or eliminate the use of plastic water bottles and plastic food packaging
  • Reduce alcohol consumption
  • Manage stress
  • Weight training
  • Hormone detoxification
  • Eat a plant-based diet
  • Supplements- Zinc, glutathione, flaxseed, vitamin B6, passion flower (chrysin)

Wells Pharmacy offers BHRT formulations for men that address the challenges of aromatization. Formulations containing estrogen blockers such as progesterone, chrysin or anastrazole (aromatase inhibitor) are available in custom dosages and combinations with testosterone and DHEA.

Schedule consultation with a pharmacist specialized in hormone therapy

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